Products that claim to control bed bugs have been on the market for years. Some work, and some don't. Dr. Susan Jones, a professor of entomology at Ohio State University, knows this as well as anyone, after having tested many such products for years. While there have been some flops in the past, she and her colleagues have found one that looks promising as a new tool for bed bug control programs. The results of their research are published in an article in the Journal of Medical Entomology.

Mattress liners sold under the trade name ActiveGuard are impregnated with an insecticide called permethrin, which is considered safe for humans and other mammals. Permethrin - which belongs to a class of pesticides called pyrethroids - is found in medical creams to treat scabies, shampoos for head lice, and it's the active ingredient in some flea-control products for dogs and cats.

In recent years, however, some bed bug populations have developed resistance to some pyrethroids and related pesticides, making them less lethal. But for Jones and her team, killing bed bugs is only one part in the effort to control them.

"Death doesn't have to be the end-point that we measure in studies," Jones says. "Physical or behavioral changes can significantly affect the impact of bed bugs before death even occurs."

One of these things is fecundity -- the bed bugs' ability to lay eggs and reproduce. In order to lay eggs, female bed bugs must first have a bloodmeal, so the Ohio researchers set out to test ActiveGuard's effects on bed bug feeding.

"Feeding in bed bugs and fecundity are very tightly coupled," Jones says. "If a female bed bug doesn't feed, then she is unlikely to lay eggs, and if she doesn't lay eggs, then the life cycle is interrupted."

Surprisingly, they found the ActiveGuard fabric to be extremely effective, even in bed bug populations that were resistant to pyrethroids. Bed bugs that were exposed to the fabric for ten minutes were significantly less likely to even attempt feeding compared to those on untreated fabric, and the majority were unable to feed successfully. Even when they were successful, their bloodmeals were only half the size of bed bugs that were not exposed to the fabric.

Even more surprising, out of 52 females tested, only one laid a single egg.

"We were totally shocked, and we were also shocked by how quickly we started seeing these sublethal effects," Jones says. "After just one minute of being on the fabric, their probing behavior was reduced, and by 10 minutes they just weren't feeding much. If a female bed bug doesn't feed, she doesn't lay eggs."

The researchers do not yet know how or why the ActiveGuard fabric affects female bed bug feeding and fecundity - it may disorient or irritate them, but at this point that is only speculation.

"We are still trying to figure out what is going on," Jones says. "That will be a future paper."

Previous research by Dr. Jones showed that ActiveGuard was very effective at killing some bed bug populations, but was less so with ones that were resistant to pyrethroids. The results of this study suggest that even sublethal exposure can have far-reaching consequences.