By HFT Staff

St. Luke's University Health Network announced its new St. Luke's Heart Hospital will be opening at St. Luke's Anderson Campus in October. The $252 million Heart Hospital is the largest construction project in St. Luke's more than 150-year history, both in terms of dollar figure and square footage. 

The five-story, approximately 355,000-square-foot facility, constructed entirely of American steel, is seamlessly integrated into St. Luke’s Anderson Campus. A central corridor on each of the upper floors stretches 330 feet — roughly the length of a football field. 

Construction began in 2024 and has employed hundreds of skilled workers. Once fully operational, the Heart Hospital will support hundreds of healthcare jobs. Despite its size and complexity, the project was completed at a relatively low per-square-foot cost by industry standards. 

Designed to support learning and innovation, the Heart Hospital furthers St. Luke's educational mission through expanded teaching space and a new cardiac fellowship program. It also incorporates numerous design innovations intended to improve efficiency and enhance patient experience. For example, internal service corridors provide staff access to supplies and other support areas, facilitating better workflow. 

The facility also includes features that will improve flow and otherwise benefit the broader Anderson Campus, including a rooftop helipad and a new, larger cafeteria.